Clopidogrel (Plavix®) is an antiplatelet drug you can take to prevent blood clots
Thrombin inhibitors inactivate free thrombin
5, 6 The standard medical treatment for ACS patients and patients receiving
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Direct Thrombin Inhibitors
Introduction
The formation of thrombin is the central link in the blood clotting process
Its mechanism of action is the irreversible inhibition of the cyclooxygenase-1 (COX1) enzyme in the arachidonic acid pathway to limit inflammation
The available GP IIb/IIIa inhibitors include tirofiban and eptifibatide
The platelet surface is where all the chain reactions in the coagulation cascade occur
Thrombin–protease-activated receptor-1 biology and rationale for thrombin receptor (protease-activated receptor-1) inhibition
This activity reviews the indications, action, and contraindications for bivalirudin as a valuable agent in the therapy of acute myocardial
Oral direct inhibitors of thrombin and activated factor Xa are approved as new anticoagulant drugs
Background—Bivalirudin, a direct thrombin inhibitor, is a widely used adjunctive therapy in patients undergoing percutaneous intervention (PCI)
Thrombosis Research
Dabigatran is an oral, specific, reversible monovalent direct thrombin inhibitor for the prevention of thrombosis, which, as a
Summary: Dabigatran (Pradaxa) is a member of the relatively new class of antithrombotic drugs known as direct thrombin inhibitors (DTIs)
Compared to warfarin, Summary and dosage of reversal agents for platelet inhibitors—aspirin, clopidogrel, prasugrel, ticagrelor and nonsteroidal anti-inflammatory drugs